Neckers, Leonard M: search on Z-Library

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1

Computational Polypharmacology Analysis of the Heat Shock Protein 90 Interactome

Anighoro, Andrew, Stumpfe, Dagmar, Heikamp, Kathrin, Beebe, Kristin, Neckers, Leonard M., Bajorath, Jürgen, Rastelli, Giulio

Journal:

Journal of Chemical Information and Modeling

Year:

2015

Language:

english

File:

PDF, 1.53 MB

english, 2015

2

Hsp90, Not Grp94, Regulates the Intracellular Trafficking and Stability of Nascent ErbB2

Wanping Xu, Edward G. Mimnaugh, Jung-Sik Kim, Jane B. Trepel and Leonard M. Neckers

Journal:

Cell Stress and Chaperones

Year:

2002

Language:

english

File:

PDF, 964 KB

english, 2002

3

NAD glycohydrolase: enzyme characterization using intact mammalian erythrocytes

Goodman, Steven I., Wyatt, Richard Jed, Trepel, Jane B., Neckers, Leonard M.

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1982

Language:

english

File:

PDF, 319 KB

english, 1982

4

Characterization of Three Monoclonal Antibodies That Recognize the Interferon α 2 Receptor

Oscar R. Colamonici, Francesco D'Alessandro, Manuel O. Diaz, Susan A. Gregory, Leonard M. Neckers and Richard Nordan

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.13 MB

english, 1990

5

In Vivo Modulation of N- myc Expression by Continuous Perfusion with an Antisense Oligonucleotide

WHITESELL, LUKE, ROSOLEN, ANGELO, NECKERS, LEONARD M.

Journal:

Antisense Research and Development

Year:

1991

Language:

english

File:

PDF, 8.31 MB

english, 1991

6

Site-Selective Cyclic AMP Analogs as New Biological Tools in Growth Control, Differentiation, and Proto-oncogene Regulation

Cho-Chung, Yoon Sang, Clair, Timothy, Tagliaferri, Paierosandro, Ally, Shamsia, Katsaros, Dionyssios, Tortora, Giampaolo, Neckers, Leonard, Avery, Thomas L., Crabtree, Gerald W., Robins, Roland K.

Journal:

Cancer Investigation

Year:

1989

Language:

english

File:

PDF, 2.24 MB

english, 1989

7

MONONUCLEAR CELL-SURFACE ANTIGENS DURING STORAGE OF BANKED BLOOD

DZIK, WALTER H., NECKERS, LEONARD

Journal:

Transplantation Journal

Year:

1984

File:

PDF, 461 KB

1984

8

Phorbol ester-induced surface transferrin receptor modulation: No correlation with decreased cell proliferation

Leonard M. Neckers, Carlos Vidal, Ronald McGlennen, Oscar Colamonici

Journal:

Experimental Cell Research

Year:

1986

Language:

english

File:

PDF, 739 KB

english, 1986

9

Induction of Differentiation in a Case of Common Acute Lymphoblastic Leukemia

Cossman, Jeffrey, Neckers, Leonard M., Arnold, Andrew, Korsmeyer, Stanley J.

Journal:

Boston Medical and Surgical Journal

Year:

1982

Language:

english

File:

PDF, 2.70 MB

english, 1982

10

Synthesis of a stable and orally bioavailable englerin analogue

Fash, David M., Peer, Cody J., Li, Zhenwu, Talisman, Ian J., Hayavi, Sima, Sulzmaier, Florian J., Ramos, Joe W., Sourbier, Carole, Neckers, Leonard, Figg, W. Douglas, Beutler, John A., Chain, William

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 543 KB

english, 2016

11

Regulation of 5-hydroxytryptamine metabolism in mouse brain by adrenal glucocorticoids

Leonard Neckers, Paul Y. Sze

Journal:

Year:

1975

Language:

english

File:

PDF, 600 KB

english, 1975

12

Requirement for adrenal glucocorticoid in the ethanol-induced increase of tryptophan hydroxylase activity in mouse brain

Paul Y. Sze, Leonard Neckers

Journal:

Year:

1974

Language:

english

File:

PDF, 214 KB

english, 1974

13

Transferrin Receptor Expression and the Control of Cell Growth

Neckers, Leonard M., Trepel, J. B.

Journal:

Cancer Investigation

Year:

1986

Language:

english

File:

PDF, 807 KB

english, 1986

14

Electroporation enhances c-myc antisense oligodeoxynucleotide efficacy

Bergan, Raymond, Connell, Yvette, Fahmy, Brigid, Neckers, Leonard

Journal:

Nucleic Acids Research

Year:

1993

Language:

english

File:

PDF, 3.11 MB

english, 1993

15

Synthesis and evaluation of 8,9-amido analogs of geldanamycin

Merritt B. Andrus, Yong Wong, Jing Liu, Kristin Beebe, Leonard M. Neckers

Journal:

Tetrahedron Letters

Year:

2009

Language:

english

File:

PDF, 397 KB

english, 2009

16

Some kinetic parameters of platelet monoamine oxidase in chronic schizophrenia

Rodger D. Kobes, Steven G. Potkin, C.David Wise, T.Peter Bridge, Leonard M. Neckers, Richard Jed Wyatt

Journal:

Psychiatry Research

Year:

1979

Language:

english

File:

PDF, 497 KB

english, 1979

17

Can the heat shock protein 90 inhibitor geldanamycin be designed to specifically inhibit HER-2 tyrosine kinase?

Leonard M. Neckers

Journal:

Drug Resistance Updates

Year:

2000

Language:

english

File:

PDF, 94 KB

english, 2000

18

Deficient helper cell function as a cause of diminished pokeweed mitogen blastogenic responses in patients with non-Hodgkin's lymphomas

Bruce A. Silver, Frieda W. Bostick-Bruton, Leonard Neckers, Richard I. Fisher

Journal:

Year:

1984

Language:

english

File:

PDF, 753 KB

english, 1984

19

Regulation of BRCA1 by protein degradation

Blagosklonny, Mikhail V, An, Won G, Melillo, Giovanni, Nguyen, Phuongmai, Trepel, Jane B, Neckers, Leonard M

Journal:

Year:

1999

Language:

english

File:

PDF, 606 KB

english, 1999

20

Lymphocyte monoamine oxidase activity and chronic schizophrenia

Lynn E. DeLisi, Leonard M. Neckers, Richard A. Staub, Steven J. Zalcman, Richard Jed Wyatt

Journal:

Psychiatry Research

Year:

1980

Language:

english

File:

PDF, 567 KB

english, 1980

21

993 FEASIBILITY AND OUTCOMES OF PARTIAL NEPHRECTOMY FOLLOWING THERAPY WITH A HEAT SHOCK PROTEIN 90 INHIBITOR

Williams, Heinric, Krill, Aaron, Fowler, Sally, Neckers, Leonard, Pinto, Peter A., Ivy, Percy, Srinivasan, Ramaprasand, Linehan, W. Marston, Bratslavsky, Gennady

Journal:

The Journal of Urology

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

22

Differential expression of c-myc and the transferrin receptor in G1 synchronized M1 myeloid leukemia cells

Leonard M. Neckers, Hiroyuki Tsuda, Ervin Weiss, Dov H. Pluznik

Journal:

Journal of Cellular Physiology

Year:

1988

Language:

english

File:

PDF, 726 KB

english, 1988

23

Interleukin-6 antisense deoxyoligonucleotides inhibit bone resorption by giant cells from human giant cell tumors of bone

Sakamuri V. Reddy, Shunji Takahashi, Mark Dallas, Ronald E. Williams, Leonard Neckers, G. David Roodman

Journal:

Journal of Bone and Mineral Research

Year:

1994

Language:

english

File:

PDF, 752 KB

english, 1994

24

bcl-2 Protein downregulation is not required for differentiation of multidrug resistant HL60 leukemia cells

Mikhail V. Blagosklonny, Manuel Alvarez, Antonio Fojo, Leonard M. Neckers

Journal:

Leukemia Research

Year:

1996

Language:

english

File:

PDF, 690 KB

english, 1996

25

Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G1 phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex

Shiotsu, Yukimasa, Neckers, Leonard M., Wortman, Ivo, An, Won G., Schulte, Theodor W., Soga, Shiro, Murakata, Chikara, Tamaoki, Tatsuya, Akinaga, Shiro

Journal:

Year:

2000

File:

PDF, 294 KB

2000

26

MP49-20 SYNERGISTIC EFFECT OF TARGETED COMBINATION THERAPY IN BLADDER CANCER MODEL USING HSP90 INHIBITORS

Chelluri, Raju, Agarwal, Piyush K., Neckers, Leonard M., Smith, Armine K.

Journal:

The Journal of Urology

Year:

2015

Language:

english

File:

PDF, 168 KB

english, 2015

27

Expression of PAX3 in Ewing's Sarcoma Family of Tumors

Theodor W. Schulte, Jeffrey A. Toretsky, Elisabeth Ress, Lee Helman, Leonard M. Neckers

Journal:

Biochemical and Molecular Medicine

Year:

1997

Language:

english

File:

PDF, 552 KB

english, 1997

28

Geldanamycin-Induced Destabilization of Raf-1 Involves the Proteasome

Theodor W. Schulte, Won G. An, Leonard M. Neckers

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 206 KB

english, 1997

29

Influence of olfactory bulbectomy and the serotonergic system upon intermale aggression and maternal behavior in the mouse

Leonard M. Neckers, M.X. Zarrow, Michael M. Myers, Victor H. Denenberg

Journal:

Pharmacology Biochemistry and Behavior

Year:

1975

Language:

english

File:

PDF, 564 KB

english, 1975

30

Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

Qing Cheng, Jeffrey T Chang, Joseph Geradts, Leonard M Neckers, Timothy Haystead, Neil L Spector, H Kim Lyerly

Journal:

Breast Cancer Research

Year:

2012

Language:

english

File:

PDF, 621 KB

english, 2012

31

Spontaneous Alteration of Idiotype in a Monoclonal B-Cell Lymphoma

Raffeld, Mark, Neckers, Leonard, Longo, Dan L., Cossman, Jeffrey

Journal:

Boston Medical and Surgical Journal

Year:

1985

Language:

english

File:

PDF, 3.19 MB

english, 1985

32

In vivo degradation of N-myc in neuroblastoma cells is mediated by the 26S proteasome

Bonvini, Paolo, Nguyen, Phuongmai, Trepel, Jane, Neckers, Leonard M

Journal:

Year:

1998

Language:

english

File:

PDF, 487 KB

english, 1998

33

Abstracts from the Fourth Annual NIH Symposium on Therapeutic Oligonucleotides: Antisense and DNA Chips

Cho-Chung, Yoon S., Beaucage, Serge, Klinman, Dennis, Marquez, Victor, Neckers, Leonard, Panyutin, Igor, Seidman, Michael

Journal:

Antisense and Nucleic Acid Drug Development

Year:

2000

Language:

english

File:

PDF, 2.99 MB

english, 2000

34

A systematic protocol for the characterization of Hsp90 modulators

Robert L. Matts, Gary E.L. Brandt, Yuanming Lu, Anshuman Dixit, Mehdi Mollapour, Suiquan Wang, Alison C. Donnelly, Leonard Neckers, Gennady Verkhivker, Brian S.J. Blagg

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

35

Measurement of the novel antitumor agent 17-(allylamino)-17-demethoxygeldanamycin in human plasma by high-performance liquid chromatography

Elizabeth B. Agnew, Richard H. Wilson, Jean L. Grem, Leonard Neckers, Daoqin Bi, Chris H. Takimoto

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2001

Language:

english

File:

PDF, 145 KB

english, 2001

36

10.1038/32925

Neckers, Leonard M., An, Won G., Kanekal, Meera, Simon, M. Celeste, Maltepe, Emin, Blagosklonny, Mikhail V.

Journal:

Year:

1998

Language:

english

File:

PDF, 372 KB

english, 1998

37

The Role of Plasmacytoma Growth Factor in the in Vitro Responses of Murine Plasmacytoma Cells

RICHARD P. NORDAN, BEVERLY A. MOCK, LEONARD M. NECKERS, STUART RUDIKOFF

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 289 KB

english, 1989

38

Cytostatic and cytotoxic activity of sex steroids against human leukemia cell lines

Blagosklonny, Mikhail V., Neckers, Leonard M.

Journal:

Year:

1994

Language:

english

File:

PDF, 537 KB

english, 1994

39

Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia.

Korsmeyer, S. J., Greene, W. C., Cossman, J., Hsu, S. M., Jensen, J. P., Neckers, L. M., Marshall, S. L., Bakhshi, A., Depper, J. M., Leonard, W. J., Jaffe, E. S., Waldmann, T. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.27 MB

english, 1983

40

[Part 1: Biological Sciences] || Rearrangement and Expression of Immunoglobulin Genes and Expression of Tac Antigen in Hairy Cell Leukemia

Stanley J. Korsmeyer, Warner C. Greene, Jeffrey Cossman, Su-Ming Hsu, Jane P. Jensen, Leonard M. Neckers, Sandra L. Marshall, Ajay Bakhshi, Joel M. Depper, Warren J. Leonard, Elaine S. Jaffe and Thoma

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.44 MB

english, 1983

41

Induction of Megakaryocytic Differentiation and Modulation of Protein Kinase Gene Expression by Site-Selective cAMP Analogs in K-562 Human Leukemic Cells

Giampaolo Tortora, Timothy Clair, Dionyssios Katsaros, Shamsia Ally, Oscar Colamonici, Leonard M. Neckers, Pierosandro Tagliaferri, Tore Jahnsen, Roland K. Robins and Yoon Sang Cho-Chung

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.12 MB

english, 1989

42

Inhibition of Heat Shock Protein HSP90-pp60v-srcHeteroprotein Complex Formation by Benzoquinone Ansamycins: Essential Role for Stress Proteins in Oncogenic Transformation

Luke Whitesell, Edward G. Mimnaugh, Brian De Costa, Charles E. Myers and Leonard M. Neckers

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.48 MB

english, 1994

43

Site-selective cyclic AMP analogs provide a new approach in the control of cancer cell growth

Dionyssios Katsaros, Giampaolo Tortora, Pierosandro Tagliaferri, Timothy Clair, Shamsia Ally, Leonard Neckers, Roland K. Robins, Yoon Sang Cho-Chung

Journal:

Year:

1987

Language:

english

File:

PDF, 448 KB

english, 1987

44

Mechanisms of Disease: the role of heat-shock protein 90 in genitourinary malignancy

Lattouf, Jean-Baptiste, Srinivasan, Ramaprasad, Pinto, Peter A, Linehan, W Marston, Neckers, Leonard

Journal:

Nature Clinical Practice Urology

Year:

2006

Language:

english

File:

PDF, 392 KB

english, 2006

45

[Part 1: Biological Sciences] || Transferrin Receptor Induction in Mitogen-Stimulated Human T Lymphocytes is Required for DNA Synthesis and Cell Division and is Regulated by Interleukin 2

Leonard M. Neckers and Jeffrey Cossman

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 813 KB

english, 1983

46

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

Heikkila, Reino, Schwab, Gisela, Wickstrom, Eric, Loke, Shee Loong, Pluznik, Dov H., Watt, Rosemary, Neckers, Leonard M.

Journal:

Year:

1987

File:

PDF, 689 KB

1987

47

Abstracts from the Third Annual NIH Symposium on Therapeutic Oligonucleotides

Cho-Chung, Yoon S., Beaucage, Serge, Marquez, Victor, Neckers, Leonard, Torrence, Paul F.

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1999

Language:

english

File:

PDF, 4.64 MB

english, 1999

48

Interaction of Radicicol with Members of the Heat Shock Protein 90 Family of Molecular Chaperones

Schulte, Theodor W., Akinaga, Shiro, Murakata, T., Agatsuma, Tsutomu, Sugimoto, Seiji, Nakano, Hirofumi, Lee, Yong S., Simen, Birgitte B., Argon, Yair, Felts, Sara, Toft, David O., Neckers, Leonard M.

Journal:

Molecular Endocrinology

Year:

1999

Language:

english

File:

PDF, 1.34 MB

english, 1999

49

Low Dose Geldanamycin Inhibits Hepatocyte Growth Factor- and Hypoxia-Stimulated Invasion of Cancer Cells

Koga, Fumitaka, Tsutsumi, Shinji, Neckers, Leonard M.

Journal:

Year:

2007

Language:

english

File:

PDF, 1.31 MB

english, 2007

50

Antisense Inhibition of Gene Expression: A Tool for Studying the Role of NMYC in the Growth and Differentiation of Neuroectoderm-Derived Cells

Neckers, Leonard M., Rosolen, Angelo, Whitesell, Luke

Journal:

Journal of Immunotherapy

Year:

1992

File:

PDF, 447 KB

1992

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